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CAS
Purity
Category
Nickname
: 67-63-0
: 99.80%
: Alcohol Ether
size/weight
:
isopropyl alcohol, chemical name 2-propanol, referred to as IPA, is a colorless and transparent liquid with a special smell, chemical formula C3H8O, molecular weight 60.10. It has good solubility and volatility, and can be miscible with water, alcohol, ether and other solvents. It is an important raw material in the fields of chemical industry, pharmacy, cosmetics and electronic industry. Isopropyl alcohol is used in the pharmaceutical industry to produce disinfectants, solvents and pharmaceutical intermediates; in the chemical industry, it is a key raw material for the production of chemicals such as acetone and hydrogen peroxide; at the same time, isopropyl alcohol is also widely used in the manufacture of coatings, printing inks and detergents. Its versatility and wide range of applications make isopropanol an indispensable raw material in industrial production.
(1) isopropanol in the chemical industry as an important raw material, can produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropyl amine, isopropyl ether, isopropyl chloride and fatty acid isopropyl ester and chlorinated fatty acid isopropyl ester and other chemical products.
(2) isopropyl alcohol as a solvent, because it can be freely mixed with water and the dissolution of lipophilic substances than ethanol, is widely used in the dissolution of nitrocellulose, rubber, paint, shellac, alkaloids, etc., but also can be used in the production of coatings, inks, extractants, aerosol agents.
(3) Isopropyl alcohol also has important applications in the pharmaceutical and cosmetic industries. It is an intermediate or solvent for many drugs and cosmetics.
(4) Isopropyl alcohol can also be used as a chromatographic standard for the determination of barium, calcium, copper, magnesium, nickel, potassium, sodium, strontium, nitrous acid, cobalt and other metal ions.
(5) In the electronics industry, isopropyl alcohol is often used as a cleaning degretizer for cleaning electronic components and circuit boards.
(6) isopropyl alcohol can also be used as antifreeze, cleaning agent, blending gasoline additives, pigment production dispersant, printing and dyeing industry fixative, glass and transparent plastic antifogging agent.
(7) In the oil industry, isopropanol can be used as an extractant for cottonseed oil, and can also be used for degreasing of animal-derived tissue membranes.
1. Packing: barreled, scattered water
2. Logistics: car transportation, shipping
3. Payment request: EXW/FOB/FCA/CFR only accepted
Chinese name | Isopropyl alcohol |
English Name | Isopropanol |
Alias | Isopropyl alcohol 2-Propanol dimethyl methanol medicinal isopropyl alcohol high purity isopropyl alcohol isopropyl alcohol standard solution isopropyl alcohol (anhydrous) 2-Propanol (Isopropyl Alcohol) 2-propanol, dimethyl methanol 2-Propanol (anhydrous isopropanol) isopropyl alcohol [for spectrophotometric determination] isopropyl alcohol, 67-63-0, Aladdin reagent |
English alias | IPA 2-Propanol Isopropanol propan-1-ol Isopropylalcohol 2-PROPANOL (IPA) Isopropyl Alcohol iso propyl alcohol isopropanol anhydrous Propan-2-ol-SPECIFIED isopropanol molecular biology 2-PROPANOL ULTRA RESI-ANALYZED |
CAS | 67-63-0 |
EINECS | 200-661-7 |
Chemical formula | C3H8O |
molecular weight | 60.1 |
InChI | InChI=1/C3H8O/c1-2-3-4/h4H,2-3H2,1H3 |
Density | 0.785g/mLat 25°C(lit.) |
melting point | -89.5°C |
boiling point | 82°C(lit.) |
Flash Point | 53°F |
water solubility | miscible |
Vapor pressure | 33mm Hg ( 20 °C) |
steam density | 2.1 (vs air) |
JECFA Number | 277 |
solubility | Water: Soluble (complete) |
refractive index | n20/D 1.377(lit.) |
acidity coefficient | 17.1(at 25℃) |
Storage conditions | Store at +5°C to +30°C. |
Appearance | low melting point solid |
Specific Gravity | approximate 0.785(20/20℃)(Ph.Eur.) |
Color | colorless |
Smell | Like ethyl alcohol; sharp, somewhat unpleasant; characteristic mild alcoholic; nonresidual. |
Maximum wavelength (λmax) | ['λ: 260 nm Amax: 0.02', , 'λ: 280 nm Amax: 0.01'] |
Merck | 14,5208 |
BRN | 635639 |
explosion limit value | 2-13.4%(V) |
Exposure Limits | TLV-TWA 980 mg/m3 (400 ppm); STEL 1225 mg/m3 (500 ppm) (ACGIH); IDLH 12,000 ppm (NIOSH). |
physicochemical properties | colorless transparent flammable liquid, like the smell of ethanol. With water, ethanol, ether, chloroform miscible. |
Dangerous Goods Signs | Xi-Irritant F-Flammable Xn-Hazardous |
Risk Terms | R11-Highly flammable. , R36-Irritating to eyes. -R67-Vapor may cause drowsiness and dizziness. -R40-Few reported carcinogenic consequences. , R10-Flammable. , R36/38-Irritating to eyes and skin. |
Security terminology | S7-Keep container sealed. , S16-Keep away from ignition sources. , S24/25-Avoid skin and eye contact. S26- After contact with eyes, rinse immediately with plenty of water and seek medical advice. , S36/37-Wear appropriate protective clothing and gloves. |
Dangerous Goods Transport Number | UN 1219 3/PG 2 |
WGK Germany | 1 |
RTECS | NT8050000 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Yes |
Customs number | 2905 12 00 |
Hazard Class | 3 |
Packing Group | II |
Upstream raw materials | propylene phosphoric acid |
Downstream Products | isopropyl acetate isopropyl palmitate |
Colorless transparent liquid. Slight smell of ethanol. It can be miscible with water, ethanol, ether and chloroform. Its vapor and air form an explosive mixture, which can cause combustion and explosion when exposed to open flame and high heat. Can react strongly with oxidants. In case of high heat, the internal pressure of the container increases, and there is a risk of cracking and explosion.
, the raw material gas containing more than 50% propylene is absorbed by 75~6 ~ 85% concentrated sulfuric acid at 50 ℃ and low pressure to produce isopropyl hydrogen sulfate. Isopropyl hydrogen sulfate is then hydrolyzed to isopropanol. After crude distillation, the distillation tower is used to concentrate to 95%, then benzene is used to extract, water is separated and then distilled, and a finished product containing more than 99% isopropanol can be obtained. Alternatively, propylene and water were pressurized to 1.96 MPa respectively. And preheated to 200 degrees C, mixed and added to the reactor, hydration reaction. After neutralization and heat exchange, the reaction gas is sent to a high-pressure cooler and a high-pressure separator. Isopropanol in the gas phase is recovered by spraying with deionized water in a recovery tower. 85% ~ 87% isopropanol aqueous solution is distilled by a crude distillation tower, concentrated to 95% by a distillation tower, and then extracted with benzene to obtain more than 99% isopropanol.
This product is 2-propanol.
The relative density (general 0601 Wechsler gravity scale method) is 0. 785~0.788.
The refractive index (general 0622) is 1. 376~1. 379.
determination of barium, calcium, copper, magnesium, nickel, potassium, sodium, strontium, nitrite, cobalt and other reagents. Chromatographic analysis standards. As chemical raw materials, it can produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropyl amine, isopropyl ether, isopropyl ether, isopropyl chloride, and fatty acid isopropyl ester and chlorinated fatty acid isopropyl ester. In fine chemicals, it can be used to produce isopropyl nitrate, isopropyl xanthate, triisopropyl phosphite, aluminum triisopropoxide, pharmaceuticals and pesticides. As a solvent, it can be used in the production of paints, inks, extractants, aerosol agents, etc. It can also be used as an antifreeze, detergent, additive for blending gasoline, dispersant for pigment production, fixing agent for printing and dyeing industry, antifogging agent for glass and transparent plastic, etc.
Rats oral LD50:5.8 g/kg. Headache, drowsiness and eye, nose and throat irritation may occur when exposed to high concentrations of steam. The staff shall be well protected and the workplace shall be well ventilated. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Prevent direct sunlight. Keep container sealed. Should be stored separately from the oxidizer.
Take 50.0ml of this product, add 100ml of water, add 2 drops of phenolphthalein indicator liquid, drop sodium hydroxide titrant (O .lm o l/L) until the pink is 30 seconds without fading, and consume sodium hydroxide titrant (0. lm o l/L) shall not exceed 1. 4ml.
Take this product 1.0ml, add water 20ml, mix well, let stand for 5 minutes, according to law inspection (general rule 0901 and general rule 0902) , the solution should be clear and colorless.
Take this product, according to ultraviolet-visible spectrophotometry (general 0401) determination, in 230nm, 250nm, 270nm, 290nm and 3l0nm wavelength absorbance shall not be greater than 0.30, 0.10, 0.03, 0.0 2 and 0.01.
Take this product 2 .0 m l, add water 8 m l, shake, place 5 minutes, the solution should be clear.
Take 50.0ml of this product, place it in a 105°C constant weight evaporating dish, evaporate it on a water bath, and then dry it at 105°C for 1 hour. The remaining residue shall not exceed 1. 0mg [0.002% (g /m l) ].
Take 10.0ml of this product, place it in a colorimetric tube, adjust the temperature to 15°C, add potassium permanganate titration solution (0.02mQl/L)0.50ml, plug tightly, shake well, and stand at 156C for 15 minutes. The pink of the solution shall not completely disappear.
Take sulfuric acid 5ml, placed in dry colorimetric Zan, cooled to 1 0V, shake while dropping 5. 0ml of this product (keep the solution temperature not higher than 20°C ) , the color of the solution and yellow No. 1 standard colorimetric solution (general rules 0901) comparison, shall not be deeper.
Take 0.50ml of this product, place it in a plug colorimetric tube, add 2,4-dinitrophenylhydrazine solution (take 2,'dinitrophenylhydrazine 50mg, add 2ml of hydrochloric acid, dilute to 50ml with carbonyl-free methanol *, shake well) lm l, plug tightly, shake well, let stand for 30 minutes, add 8ml of pyridine, 2m l of water and potassium hydroxide-methanol solution (take 15ml of 33% potassium hydroxide solution, add 50ml)2ml of carbonyl-free methanol, shake well, stand for 30 minutes, dilute to 25ml with carbonyl-free methanol, shake well, and the resulting dark red and carbonyl compound (CO) impurity standard solution®0. 50ml shall not be deeper after treatment according to the same method.
Take this product, according to the moisture determination method (general 0832 the first method 1) determination, moisture content shall not exceed 0 .2%.
According to gas chromatography (general 0521).
Pharmaceutical excipients, solvents.
Shading, airtight preservation.
Isopropyl alcohol is a colorless and transparent liquid with a pungent odor at room temperature. It has a low boiling point and density, soluble in water, alcohols and ether solvents. Isopropanol is a polar solvent that can be used to dissolve many organics.
isopropyl alcohol has a variety of applications. It is an important intermediate in the synthesis of chemicals and can be used to synthesize esters, ethers and alcohols. Isopropanol is also a common choice for industrial use as a solvent and cleaning agent.
Colorless transparent liquid, similar to ethanol and acetone mixture
to the smell of the substance, can be miscible with alcohol, ether, chloroform and water, can dissolve alkaloids, rubber, shellac, rosin, synthetic resin and other organic and some inorganic substances, and water to form an azeotrope, insoluble in salt solution. At room temperature, it can start to burn, and the mixture of steam and air can easily form an explosive mixture.
isopropanol is prone to peroxide production and sometimes requires identification prior to use. The method is: take 10% isopropanol, add 1ml of 0.5 potassium iodide solution, 1:5 dilute hydrochloric acid ML and several drops of starch solution, shake well for 1 minute, if blue or blue-black is peroxidation. It is similar to ethanol and propanol, but has the properties of a secondary alcohol.
Isopropyl alcohol is a colorless and transparent organic compound, its preparation method mainly has the following several kinds:
1. from isopropionaldehyde
reduction: isopropionaldehyde and reducing agent (such as hydrogen, metal sodium, etc.) reaction, at the appropriate temperature and pressure conditions, can be prepared by isopropanol.
2. from propylene preparation: propylene and water heating reaction, the hydrated propionaldehyde, and then through the dehydration reaction, can be prepared isopropanol.
3. from propyne gas preparation: propyne gas is subjected to catalytic hydrogenation reaction to obtain propylene, and then according to the above method to prepare isopropanol.
molecular structure data
molar refractive index: 17.44
molar volume (m3/mol):75.9
isotonic capacity (90.2K):165.6
surface tension (dynes/cm):22.6
polarizability (10-24cm3):6.91
calculated Chemical Data
hydrophobic parameter calculation reference value (XlogP):0.3
number of hydrogen bond donors: 1
number of hydrogen bond acceptors: 1
number of rotatable chemical bonds: 0
topological Molecular Polar Surface Area (TPSA):20.2
number of heavy atoms: 4
surface charge: 0
Complexity: 10.8
Isotope Atomic Number: 0
to Determine Atomic Stereo Center Number: 0 Uncertain Atomic Stereo Center Number: 0
to Determine Chemical Bond Stereo Generation Center Number: 0 Uncertain Chemical Bond Stereo Generation Center Number: 0
to
Covalent Bond Unit Number: 1
isopropyl alcohol is an organic solvent, which has certain toxicity and harmfulness. The following are about the hazards of isopropyl alcohol and protective measures:
hazards:
1. Irritating effect on skin and eyes, may cause redness, burning pain and inflammation;
2. Excessive inhalation of isopropyl alcohol vapor may cause dizziness, nausea, vomiting, difficulty breathing, and nervous system damage;
3. Long-term exposure or high intake of isopropyl alcohol may cause damage to the liver, kidneys and central nervous system.
Protective measures:
1. When using isopropyl alcohol, wear protective gloves, safety goggles, protective clothing and other protective equipment to avoid contact with skin and eyes;
2. When using isopropyl alcohol in a closed environment, ensure good ventilation to avoid inhaling excessive vapor;
3. Avoid contact with fire sources, high temperature substances or oxidants, isopropyl alcohol is flammable;
4. When a leak occurs, the source of the leak should be stopped immediately, and the appropriate adsorbent should be used for adsorption and cleaning;
5. Properly store isopropyl alcohol and avoid mixing with other chemicals.
Isopropanol is an organic solvent, which is also widely used in chemical reactions and industrial production. According to market demand, the supply and demand of isopropanol has been in balance.
demand, isopropyl alcohol is mainly used in coatings, cleaning agents, glue and other industries. With the development of the global economy and the increase of industrial manufacturing, the demand for isopropyl alcohol in these fields is also increasing. Especially in the automotive industry, building materials and art protection, the demand for isopropyl alcohol has increased.
the
supply side, the production of isopropanol is mainly carried out by synthesis. At this stage, many countries and regions in the world have isopropanol production capacity, such as the United States, China, Germany and so on. Among them, China is one of the largest producers of isopropanol.
1. nature:
isopropyl alcohol is colorless transparent liquid, with special alcohol smell. It is soluble in water and a variety of organic solvents, such as
ether, methanol and alcohols. 3. Isopropyl alcohol is flammable and can form an explosive mixture with oxygen.
Uses:
Isopropanol is widely used in industrial fields, especially as a solvent for coatings, inks, resins and dyes. 2. Isopropanol in the preparation of certain chemicals
act as a reducing agent or catalyst. 3. In the laboratory, isopropyl alcohol is also commonly used as a general organic solvent.
preparation method:
of isopropyl alcohol can be prepared by the following two methods:
of 1. from propylene deoxygenation preparation: propylene at high temperature catalytic hydrogenation, generate isopropyl alcohol.
, 2. from acetone reduction preparation: acetone and hydrogen in the presence of catalyst reaction, the formation of isopropanol.
Safety Information: 1. Isopropyl alcohol is irritating and should avoid direct contact with skin and eyes.
2. in the operation of isopropyl alcohol, should pay attention to avoid inhalation of its vapor, so as not to cause poisoning. 3. with flammability, should be away from open flame and high temperature area, storage should be sealed preservation.
4 in the treatment of isopropyl alcohol waste liquid, need to take appropriate protective measures to prevent environmental pollution.
Have Doubts Regarding This Product ?
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
In the event of fire, wear self-contained breathing apparatus.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Do not let product enter drains. Risk of explosion.
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.
For disposal see section 13.
Avoid generation of vapours/aerosols.
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Change contaminated clothing. Wash hands after working with substance. For precautions see section 2.2.
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Handle and store under inert gas. Hygroscopic.
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 480 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Chloroprene
Minimum layer thickness: 0,65 mm Break through time: 120 min Material tested:KCL 720 Camapren?
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Minimum ignition energy
0,65 mJ
Conductivity < 0,1 μS/cm
Surface tension 20,8 mN/m at 25,0 °C
Relative vapor density
2,07
Vapors may form explosive mixture with air.
Reacts with air to form peroxides.
The product is chemically stable under standard ambient conditions (room temperature) .
No data available
Warming.
Acid anhydrides, Aluminum, Halogenated compounds, Acids, Strong oxidizing agents
In the event of fire: see section 5
(OECD Test Guideline 203)
EC50 - Daphnia magna (Water flea) - 13.299 mg/l - 48 h Remarks: (IUCLID)
Remarks: (IUCLID)
Remarks: (Lit.)
Biodegradability aerobic - Exposure time 5 d
Result: 53 % - Readily biodegradable. (Directive 67/548/EEC, Annex V, C.6)
Theoretical oxygen demand
2.400 mg/g Remarks: (Lit.)
Ratio BOD/ThBOD 49 %
Remarks: (IUCLID)
No bioaccumulation is to be expected (log Pow <= 4).
No data available
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
No data available
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
Incompatibilities
Incompatible with oxidizing agents such as hydrogen peroxide and nitric acid, which cause decomposition. Isopropyl alcohol may be salted out from aqueous mixtures by the addition of sodium chloride, sodium sulfate, and other salts, or by the addition of sodium hydroxide.
ADR/RID: 3 IMDG: 3 IATA: 3
ADR/RID: II IMDG: II IATA: II
ADR/RID: no IMDG Marine pollutant: no IATA: no
No data available
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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